Molecule Mattress Review

MOLECULE might be one of the newer brands on the sleep scene, but they’ve already set themselves apart with a doctor-designed line of mattresses that caters to active people looking for a restorative sleep experience.

Discover what makes MOLECULE mattresses stand out in a sea of sleep solutions, how they stack up against other popular options, plus how you can rest easy with their class-leading 365-night risk-free trial.

Last Updated April 2024

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Firmness: Medium Firm
Sizes: Twin, Twin XL, Full, Queen, King, Cal King
Materials: Foam, Hybrid
Design: Three proprietary foam layers and a moisture-wicking cover.
Trial Period: 365 nights
Warranty: Lifetime warranty
Shipping: Free shipping & returns

What is the MOLECULE mattress?

Sleep is an essential part of our day, especially for athletes and active individuals who need the downtime to recover. 

MOLECULE is the first sleep system specifically designed to prioritize restful and restorative sleep so you can maximize your energy during the day. 

Developed with the help of renowned sleep doctors and neurologists, all MOLECULE mattresses are constructed with the highest-quality foam and engineered to optimize airflow and efficiently transfer heat away from the body for the best recovery-focused sleep.

MOLECULE offers three mattress options to choose from:

    • MOLECULE 1: Includes all the essential features like pressure relief, self-adjusting support, and spine alignment—at an affordable price 
    • MOLECULE 2 AIRTEC™: Includes upgraded zoned support and temperature regulating technology, plus Microban® antimicrobial technology  
  • MOLECULE Hybrid Mattress: The most premium mattress offering multiple layers of optimal comfort and temperature regulation

MOLECULE Mattress Construction

MOLECULE employs proprietary manufacturing processes and the highest quality materials to make their eco-friendly mattresses. 

Mattress Material

The MOLECULE mattress is made up of 100 percent polyurethane foam that is made in the USA and is CertaPUR-US® certified, which means the foam is made without ozone depleters, formaldehyde, mercury, lead and heavy metals. The foam is also low VOC (Volatile Organic Compound) emissions to reduce off-gassing and improve indoor air quality. 

Mattress Type

The MOLECULE mattress is made up of multiple layers of high-quality foam specifically engineered to reduce body temperature and produce restorative sleep. 

Mattress Firmness

All MOLECULE mattresses fall within the medium firm range, with a softer top layer for added comfort and a firmer middle for ideal support. 

Age and Lifestyle 

The MOLECULE mattress is made for everyone! There is no age or weight limit, but it is especially beneficial for people who live active lifestyles and are looking to restore, recover, and ready their bodies for whatever is next. 

Sleep Position Preference

The MOLECULE mattress is best for: Side, combo and back sleepers.

Its all-foam construction gently contours to your body, providing the hip and shoulder support you need for proper spinal alignment. 

Due to the medium-firmness level of the mattress, stomach sleepers may want a little more softness to suit their preferred sleep position. 

How to Get the MOLECULE Mattress

The MOLECULE mattress is available exclusively online to savvy sleepers within the United States. Select the right mattress for you and enjoy free shipping right to your door. You have up to a year—that’s 365 sleeps—to try it out and still get your money back. 

MOLECULE 1 Mattress Pricing:

Pricing varies depending on the mattress model and size you choose, as well as current sales or promotions. At the time of this review, here’s what the pricing structure looks like:

Twin: $699

Twin XL: $699

Full: $799

Queen: $899

King: $1099

Cal King: $1099

MOLECULE partners with Klarna to provide flexible financing options—approved buyers can make monthly payments interest-free.

MOLECULE Mattress Performance

MOLECULE was founded on the belief that active bodies need more than just rest, they need repair. Their mattresses are meticulously engineered to maximize comfort, support and temperature regulation to promote restorative sleep and optimize performance. 

Motion Isolation

Due to its multiple layers of high-quality foam, the MOLECULE mattress does an excellent job of isolating motion with minimal bounce. So, if you have a partner who moves around a lot, you can still sleep soundly with MOLECULE. 

Pressure Relief

MOLECULE’s proprietary foam features exceptional pressure relief with multiple zones providing hyper-targeted, self-adjusting support that gently conforms to your shoulders and hips to promote proper spinal alignment.

Temperature Control

While memory foam mattresses have a reputation for retaining heat, the MOLECULE mattress was thoughtfully designed to maximize airflow and facilitate cooling in each layer of construction—providing up to seven times more airflow than traditional memory foam. 

The covers across all models feature a unique combination of heat and moisture-wicking technologies, and each layer of foam is specially constructed to efficiently transfer heat away from the body, which is a key factor in promoting the most restorative sleep possible. 

Edge Support

While the MOLECULE hybrid mattress is reinforced with an additional layer of foam featuring an individually wrapped coil system for extra edge support, the MOLECULE 1 and 2 mattresses are more like traditional foam mattresses in their soft edge support. This may be particularly noticeable for people who tend to sit or sleep near the edge of the bed. 

Ease of Movement

The extra soft top layer on the MOLECULE mattress that closely “hugs” your body to promote exceptional pressure relief can also make it more challenging to easily change positions. 


MOLECULE employs carefully sourced materials including high-quality CertiPUR-US® foam, and proprietary production practices to ensure their mattresses are made to last. 


The all-foam MOLECULE mattress isolates movements keeping noise to a minimum to ensure quiet comfort all night long.


With exceptional motion isolation and a near-silent sleep surface, the MOLECULE mattress provides the traction couples want while helping them to stay discreet when needed. Like most foam mattresses, it lacks the bounce and edge support of a hybrid or traditional coil-spring mattress, which can make it more challenging to easily switch positions. 


MOLECULE utilizes a proprietary manufacturing process and superior materials to minimize or even eliminate off-gassing, so you don’t have to worry about “airing out” your mattress before you use it. 

Their mattresses are made of CertiPUR-US certified foam, free of ozone depleters, formaldehyde, mercury, lead and heavy metals, and they have low VOC (Volatile Organic Compound) emissions.

MOLECULE vs Other Mattresses

Through proprietary production processes, high-quality materials, and decades of research, the team at MOLECULE (and their expert sleep specialist partners), have created the only mattress that prioritizes recovery-focused sleep to fuel your peak performance.  

MOLECULE vs Casper

While the MOLECULE 1 mattress has a similar three-layer construction to the Casper Original mattress, unlike the Casper, MOLECULE mattresses are completely latex-free. The MOLECULE 1 also comes in at a lower price point across sizes, and all MOLECULE mattresses feature an extended 365-night, risk-free trial and lifetime limited warranty compared to Casper’s 100-night trial and 10-year limited warranty, providing exceptional value for your money.     

MOLECULE vs Purple

Both MOLECULE and Purple mattresses are backed by sound science and medical expertise, but their construction differs. MOLECULE’s all-foam mattresses are made up of multiple layers of temperature-regulating foam that provide a firmer feel of support from head to toe, while Purple features a patented hyper-elastic polymer grid as the top layer of their mattresses that has a slightly softer side. MOLECULE is more competitively priced than Purple and also offers a more generous trial and warranty. 

MOLECULE Company Information

Introduced in 2018, the MOLECULE is a one-of-a-kind mattress meant for athletes and everyday active individuals that provides targeted temperature regulation and promotes slow wave sleep for the most restorative rest possible. This innovative sleep system was the brainchild of the MOLECULE team plus renowned sleep experts and neurologists with whom they partnered.

MOLECULE Customer Service Information

Sleep easy knowing that the MOLECULE Customer Success team is ready to help.

  • Call: 1-833-365-REST (1-833-365-7378)

MOLECULE Trial & Warranty Policies

MOLECULE offers some of the most generous trial and warranty terms on the market today—so you can rest assured that even if you change your mind months after your purchase, you are covered.

With MOLECULE, you have up to 365 nights from the date of delivery to request a refund. They do require you to keep the mattress for at least 30 days to allow your body enough time to adequately adjust to the mattress before starting a return. 

MOLECULE also offers a class-leading limited lifetime warranty that lasts as long as you own the mattress. 

Bottom Line

There’s a reason why elite athletes like Russell Wilson, Alex Morgan, and Michael Phelps are singing the praises of the MOLECULE mattress and its ability to help them repair and restore their bodies to promote peak performance. 

With proprietary technology backed by decades of research and the highest quality production standards, MOLECULE mattresses offer more than just rest and relaxation. 

Their competitive pricing, impressive 365-night trial, and lifetime warranty make it easy to see why anyone would choose MOLECULE for the kind of restorative sleep that dreams are made of.  


Where can I try the MOLECULE mattress?

MOLECULE offers a fully virtual shopping experience, which means they’re not in retail stores yet. But with their extended 365-night risk-free trial, you can sleep soundly knowing you’ll receive a refund if it doesn’t work for you.

Which is better, Casper or MOLECULE?

There is no definitive answer to this question since it depends on individual preferences. Some people find Casper mattresses to be more comfortable, while others prefer the medium-firmness of the MOLECULE mattresses for added support. However, both brands offer high-quality products that are designed to provide a good night’s sleep. Ultimately, the best mattress for you is the one that meets your personal needs and preferences.

What is the difference between MOLECULE 1 and 2?

  1. MOLECULE 1 mattresses are designed to provide the support, comfort and heat control you want at a price just as nice. The three layers of top-grade foam work together to both cradle and cool your body, featuring special gel-infused foam on the top layer for exceptional pressure relief and an innovative “zoned” construction in the middle that offers targeted, self-adjusting support to promote spine alignment, all supported by a fim base for extra back support. 
  2. MOLECULE 2 Airtec™ mattresses takes it up a notch with four layers of foam, featuring a special Antimicrobial cooling cover, plus proprietary technology that promotes restorative sleep at a cellular level. The MOLECULE 2 also includes Airtec technology that forms a matrix of open cells for unprecedented airflow. The result is a mattress that’s specifically designed to help you sleep clean, cool and comfortable. 

Where is MOLECULE mattress made?

MOLECULE mattresses feature CertiPUR foam manufactured in the U.S. to the strictest quality and environmental standards. 

Is MOLECULE mattress non-toxic?

MOLECULE mattresses are one of the most eco-friendly options on the market. They are non-toxic and made from proprietary foam that is 100 percent CertiPUR-US certified, which means the foam is completely free of ozone depleters, formaldehyde, mercury, lead and heavy metals. The foam in MOLECULE mattresses is low VOC (Volatile Organic Compound) emissions, meaning they won’t off-gas harmful chemicals into your environment.

MOLECULE takes it one step further by employing a patented technology during the production process that further reduces emissions by 97 percent versus standard manufacturing. This process also helps to remove off-gassing and the need to “air-out” the mattresses before use. 


The Consumer Rating Difference

Behind Our Best Mattress Ratings

We make finding the best mattress easy with expert reviews and rankings. Here’s the methodology behind our ratings:


Exhaustive Research

From the optimal firmness for side sleepers to the most effective cooling technology, we dive deep into the data to determine the best option for every kind of sleeper.

Mattress Reviews

No one knows the pros and cons of a mattress like the people sleeping on it. We read thousands of customer reviews to determine which mattresses customers like best.

Personal Experience

Our experts personally test out each top mattress, keeping in mind the features consumers care about most—like materials, design, cooling and firmness.

Side-by-Side Comparisons

From Saatva to DreamCloud, Nectar to Molecule, we compare the best mattresses across a number of key criteria to determine how each one ranks.